NAF Ataxia Research Studies Currently Underway
The following received research grant funding from the National Ataxia Foundation for the fiscal year of 2007. A summary of the completed research studies will be published in Generations in 2008.
- Deranged Calcium Signaling in SCA 3 Neurons, Ilya Bezprozvanny, PhD
- Identification of the gene responsible for a novel form for congenital cerebellar ataxia, Alfredo Brusco, PhD
- Molecular Characterization of Purkinje cell function in mice carrying deletions of the SCA 8 ataxia locus, Michael D Koob, PhD
- Spinocerebellar ataxia type 12 (SCA 12): Investigate PP2A regulation of Group I metabotropic receptors, Elizabeth O'Hearn, MD
- A Multicenter Pilot Study of the Web-Based National Ataxia Database, Susan L Perlman, MD
- Generation of improved mouse models of Friedreich ataxia for pharmacological testing, Joseph P Sarsero, PhD (B.Sc. Honrs)
- Regulatory analysis of Friedreich ataxia locus using BAC genomic reports, Joseph P Sarsero, PhD (B.Sc. Honors)
- Examination of the underlying mechanism of p53 mediation of the ataxia-telangiectasia mutant (ATM) signaling pathway, Hayla K Sluss, PhD
- The Role of the human P/Q Type Calcium Channel in the Pathogenesis of Ataxia, Sian D Spacey, MD
- Effects of Polyglutamine Expansion on Activity of Ataxin-3, the Spinocerebellar Ataxia 3 Disease Protein, Sue M Travis, PhD
- A Drosophila Model of Ataxia-Telangiectasia, David A. Wassarman
- Phosphorylation of Ataxin3-implication for cellular localization and viability, Prof. Dr. Med. U. Wullner, MD, PhD
- DNA structure of GAA*TTC repeats as a target for Friedreich's ataxia therapy, Marek Napierala, PhD
- Molecular mechanism of transcription alterations in SCA 1, Marija Cvetanovic, PhD
- The role of P/Q calcium channel fragments in SCA 6 pathogenesis, Yuanxin Hu, PhD
- Development of Histone Deacetylase Inhibitors as Therapeutics for Friedreich's Ataxia, Elisabeth Soragni, PhD
