RESEARCH GRANT AWARD SUMMARIES
The following received research grant funding from the National Ataxia Foundation for the fiscal year of 2009. A summary of the completed research studies were published in the Fall 2010 issue of Generations:
- Alternative Splicing in SCA1, Smita Agrawal, PhD
- Investigate the DUB activity of Ataxin-3 and its effect on parkin stability and activity, Thomas, M. Durcan, PhD
- Spinocerebellar ataxia 2: cellular and molecular action of normal and mutant ataxin-2, Stefan Kindler, PhD
- Manipulation of frataxin expression in neurons, Filip Lim, PhD and Richard Wade-Martins, PhD
- The identification of putative drug targets for SCA3 using Drosophila melanogaster, Leeanne McGurk, PhD
- Cellular mechanisms underlying SCA1 pathogenesis, Puneet Opal, MD, PhD
- Spinocerebellar Ataxia: Three novel genetic forms, Shirley Rainier, PhD
- Preclinical Markers of Cardiomyopathy in Friedreich”s Ataxia, Subha V. Raman, M.D. and Roula al-Dahhak, M.D.
- Development of Methods to Determine the Pharmacodynamic Effect of HDAC Inhibitors on Frataxin Expression, James R. Rusche, PhD
- Role of small heat shock proteins (HspB) in the prevention of mutant ataxin-3 aggregation and toxicity, Carra Serena, PhD
- Looking for gross rearrangements of CACNA1A gene in Episodic Ataxia type 2 (EA2) patients by Comparative Genomic Hybridization (CGH) arrays, Liana Veneziano, PhD
- A Pilot, Randomized, Double-blind, Placebo-controlled Phase I Study to Determine the Safety and Tolerability of a compound in Treating Spinocerebellar Ataxia Types 3, Theresa A. Zesiewicz, MD
