Research Grant Award Summaries
The following received research grant funding from the National Ataxia Foundation for the fiscal year of 2010. A summary of the completed research studies will be published in Generations in 2011:
- New initiative for clinical research on ataxia, S. H. Subramony, MD
- Optimizing delivery of frataxin using cell penetrant peptides, Ronald Mark Payne, MD
- Screening for mitofunctional Friedreich’s Ataxia therapeutics, Gino A. Cortopassi , PhD
- Molecular function of senataxin protein, defective in ataxia oculomotor apraxia type 2 (AOA2), in regulation of human gene expression, Natalia Gromak, PhD
- Cerebrospinal fluid biomarkers in spinocerebellar ataxia. Christopher Gomez, MD, PhD
- Identifying common genetic modifiers of Spinocerebellar ataxias (SCAs) using Drosophila model Keyi Zhu, MD, PhD
- Identification of compounds that modulate ataxin-3 aggregation and neurological dysfunction in a C. elegans model of Machado-Joseph disease, Patrícia Maciel, PhD
- Modulation of autophagy as a novel therapeutic strategy for Machado-Joseph disease, Luís Pereira de Almeida, PhD
- Understanding the role of altered physiology in the pathogenesis of SCA3, Vikram G. Shakkottai, MD, PhD
- Understanding the ubiquitin code in disease: from protein function to protein aggregation, Sandra de Macedo Ribeiro, PhD
- Molecular Mechanisms of Beta 3 Spectrin in Spinocerebellar Ataxia 5 (SCA5), Michael Stankewich, PhD
- Regulation of neuronal genes by the alpha1A C terminus of Calcium channel and disruption in SCA6, Xiaofei Du, MD
- Deconstructing the transcriptional dysregulation of Spinocerebellar ataxia type 7 retinal degeneration, Paula Ladd, PhD
- Biorepository (tissue bank) of specimens for ataxia research, Arnulf H. Koeppen, MD
