Polyglutamine expansion diseases, also known as CAG triplet repeat disorders, are a group of neurodegenerative diseases caused by extra glutamine repeats being added into proteins. This group includes SCA1, SCA2, SCA3, SCA6, SCA7, SCA17, Huntinton’s Disease (HD), Spinal and bulbar muscular atrophy (SBMA), and Dentatorubropallidoluysian atrophy (DRPLA).
For more information on polyglutamine expansion diseases, see our article categories on the subject.
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