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SCA3

Snapshot: What are oligodendrocytes?

Oligodendrocytes are a type of brain cell that play a crucial role in insulating neurons to facilitate efficient transmission of electrical signals. Similar to the rubber coating on cords, oligodendrocytes wrap around axons with a cholesterol-rich myelin structure, which speeds up the transmission of electrical impulses. Each oligodendrocyte can myelinate Read More…

Getting ready for trials in SCA1 and SCA3 with imaging

Written by Dr. Gülin ÖzEdited by Dr. Celeste Suart Advanced Magnetic Resonance Imaging (MRI) detects brain changes before ataxia symptoms. The list of pharmaceutical companies that turned their attention to ataxias has been steadily increasing over the last decade. This is in large part thanks to exciting developments in gene Read More…

Um esforço contínuo em direção ao tratamento da SCA3

Escrito por Dr. Jorge Diogo Da Silva Editado por Dr. David Bushart Traduzido para o português por Priscila Pereira Sena Como um grupo de pesquisa avaliou se a Rivastigmina, uma droga usada no tratamento da doença de Parkinson, pode exercer um papel no tratamento da SCA3 Ataxia Espinocerebelar do tipo Read More…

Ataxina-3 e a disputa entre a reciclagem mitocondrial e a morte celular

Escrito por Kaitlyn Neuman Editado por Dra. Chandana Kondapalli Traduzido para o português por Priscila Pereira Sena Induzir a morte celular ou degradar mitocôndrias adoecidas – essa é a questão: um novo papel da ataxina-3 como mediadora dessa decisão. Você já ouviu alguém dizer: “Eu posso parecer não estar fazendo Read More…

Snapshot: What is the Medulla Oblongata?

The nervous system is made up of two main components: the central nervous system, which consists of the brain and the spinal cord, and the peripheral nervous system, which consists of nerve cells that branch off the spinal cord and connect the central nervous system to the rest of the Read More…

A Continuous Effort Towards Treatment of SCA3

Written by Dr. Jorge Diogo Da Silva Edited by Dr. David Bushart How one research group assessed whether Rivastigmine, a Parkinson’s Disease drug, might have a role in treating SCA3 Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD), is the most common inherited ataxia worldwide. As with Read More…

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