Written by Kaitlyn NeumanEdited by Dr Chandana Kondapalli To induce cell death, or to degrade sick mitochondria – that is the question: a new role for ataxin-3 as a mediator of this decision. Have you ever heard the saying: “I may look like I’m not doing anything, but on a Read More…
Written by Ronald Buijsen Edited by Celeste Suart The Late Breaking Session presents data that are high-impact, groundbreaking, innovative, and newsworthy. This session will cover insights into FA disease mechanisms, a novel screening platform and the use of natural history data in clinical trials. After announcing the ICAR 2022 award Read More…
Written by Dr. Amy Smith-Dijak Edited by Celeste Suart Let’s talk treatment. Thursday afternoon starts off with some debates about testing and administering new therapies. Later attendees will hear about the latest clinical trials for ataxia therapies. Work with patients? There is also a workshop on the SARA scale. Thursday Read More…
Written by Dr. Jorge Diogo Da Silva Edited by Celeste Suart This morning’s session looks beyond traditional drugs to new and innovative approaches for ataxia treatment, the best platforms to research ataxia in the lab, and the best symptom and quality of life scales to test them in patients. On Read More…
Written by Dr. Hannah Shorrock Edited by Celeste Suart Understanding non-motor functions and factors that govern differential vulnerability in the cerebellum will help to inform preclinical therapy development, from CRISPR to small molecules, and provides important considerations for imaging studies. The Wednesday afternoon series of talks at ICAR will begin Read More…
Written by Sarah Donofrio and Dr. Hannah ShorrockEdited by Celeste Suart This morning ICAR speakers will discuss the processes in the brain and body that occur in ataxia. Talks will also include potential biomarkers for ataxia and neuroimaging techniques used to understand the disease. The morning session on November 2nd Read More…
Written by Dr. Hannah Shorrock and Sarah Donofrio Edited by Celeste Suart Developing innovative imaging techniques and leveraging a clear understanding of disease mechanisms will pave the way for clinical trial success in the ataxias. We will discuss cutting-edge research findings on these topics this afternoon! This session will feature Read More…
Written by Celeste Suart Edited by Dr. Hayley McLoughlin The first-ever International Congress for Ataxia Research is starting today! Want to learn more about what is happening at the meeting? This week, SCAsource and the National Ataxia Foundation will be posting Conference Previews of the sessions at ICAR. These previews Read More…
Brainstem – the part that connects and acts as a communicator between our brain and our spinal cord. The brainstem itself is composed of midbrain, pons, and medulla oblangata. Even minor injuries or disruptions to this neural communication and this region can have devastating consequences. The pons is a horseshoe-shaped Read More…
Written by Dr Hannah K Shorrock Edited by Dr Vitaliy V Bondar Measuring levels of polyQ ATXN3 proteins in cerebrospinal fluid and plasma distinguishes SCA3 patients from unaffected individuals For disease-modifying medicines or therapies to be approved for use in the clinic, the treatments must demonstrate success at meeting pre-set Read More…
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