Written by Paige Blair Edited by Larissa Nitschke & Celeste Suart What are adeno-associated viruses? Adeno-associated viruses, also known as AAV, are a type of virus that infects humans without Read More…
Written by Dr. Jorge Diogo Da Silva Edited by Dr. David Bushart How one research group assessed whether Rivastigmine, a Parkinson’s Disease drug, might have a role in treating SCA3 Read More…
Escrito por Carrie SheelerEditado por Dr. Hayley McLoughlin e traduzido para o português por Priscila Pereira Sena Pesquisadores usam ressonância magnética (RM) para determinar se o volume cerebral pode ser Read More…
Written by Dr. Ronald BuijsenEdited by Celeste Suart The Late Breaking Session presented data on new insights into FA disease mechanisms and positive results in an FA omaveloxolone clinical trial, Read More…
Written by Dr. Amy Smith-Dijak, with notes from Dr. Jorge Diogo Da Silva and Celeste SuartEdited by Hayley McLoughlin From debates about studying therapies, to training with an important clinical Read More…
Written by Dr. Jorge Diogo Da Silva, with notes from Sarah Donofrio and Celeste SuartEdited by Hayley McLoughlin From drugs and gene therapy, to electrical current and exercise programs: how Read More…
SCAsource began as a website where research on SCAs and related Ataxias is written in plain language by SCA scientists. Their goal was to make research more readily accessible and understandable to Ataxia patients and families. The idea for SCAsource came from discussion at the 2018 Ataxia Investigators Meeting run by NAF. The original website, scasource.net, was officially launched on September 27, 2018. It was run entirely by volunteers, primarily graduate students and post-doctoral fellows in laboratories which study Spinocerebellar Ataxias. In 2022, NAF partnered with SCAsource and its writers to host their content and publish their articles.
PhD Student with Dr. Ray Truant
McMaster University, Canada
Bio: Celeste Suart is a PhD student with Dr. Ray Truant’s group at McMaster University, Canada. She obtained her BHSc in Biomedical Discovery and Commercialization from McMaster University. Her current work focuses on characterizing the response of ataxin-1 (the protein affect in SCA1) to DNA damage and reactive oxygen species stress.
Assistant Professor
University of Michigan
Bio: Dr. Hayley McLoughlin is an Assistant Professor in the University of Michigan Neurology Department, with a joint appointment in the Department of Human Genetics. She earned her Neuroscience doctoral degree in 2013 from the University of Iowa in Dr. Beverly Davidson’s laboratory and completed a postdoctoral research fellowship under the guidance of Dr. Henry (Hank) Paulson at the University of Michigan. Her lab currently focuses on establishing pathogenic mechanisms and therapeutic interventions for neurodegenerative diseases with particular emphasis toward the polyglutamine disease, SCA3.
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Written by Dr. Jorge Diogo Da Silva Edited by Dr. David Bushart How one research group assessed whether Rivastigmine, a Parkinson’s Disease drug, might have a role in treating SCA3 Read More…
Escrito por Carrie SheelerEditado por Dr. Hayley McLoughlin e traduzido para o português por Priscila Pereira Sena Pesquisadores usam ressonância magnética (RM) para determinar se o volume cerebral pode ser Read More…
Written by Dr Hannah K Shorrock Edited by Dr Larissa Nitschke Splice modifying compounds can regulate whether or not gene therapy is active Gene therapy is an incredibly versatile therapeutic Read More…
Written by Paige Blair Edited by Larissa Nitschke & Celeste Suart What are adeno-associated viruses? Adeno-associated viruses, also known as AAV, are a type of virus that infects humans without Read More…
Brainstem – the part that connects and acts as a communicator between our brain and our spinal cord. The brainstem itself is composed of midbrain, pons, and medulla oblangata. Even Read More…
Many daily tasks, such as writing or buttoning a shirt, require fine motor skills. One aspect of fine motor skills is muscle strength. In order to write, for example, you Read More…
Principal Investigator: Dr. Marija Cvetanovic Location: University of Minnesota, Minneapolis, USA Year Founded: 2012 What disease areas do you research? SCA1 What models and techniques do you use? Mouse models Human stem Read More…
Location: University of Minnesota, MN, USA Year Research Group Founded: 2008 What disease areas do you research? Ataxia (SCA1, SCA2, SCA3, SCA6, Friedreich Ataxia) Multiple System Atrophy – Cerebellar Ataxia Huntington’s Read More…
Principal Investigator: Dr. Sheng-Han Kuo Location: Columbia University, New York, NY, United States Year Founded: 2012 What disease areas do you research? SCA1 SCA2 SCA3 SCA6 Tremor Essential Tremor What models and Read More…
Written by Terry Suk Edited by Dr. Hayley McLoughlin In this classic article, researchers describe how CAG repeat number variation can inform differences in the way SCA3/MJD symptoms present. Machado-Joseph Read More…
Written by Siddharth Nath Edited by Dr. Ray Truant Spinocerebellar ataxia type 7 (SCA7) is unique amongst the SCAs in that it involves an organ besides the brain – the eye. Rather Read More…
Written by Dr. Sriram Jayabal Edited by Dr. Brenda Toscano-Marquez Scientists uncover SACS, a gene containing the largest exon identified in vertebrates, which leads to ARSACS when mutated. What is Read More…
The SCAsource team is excited to announce that we are partnering with the National Ataxia Foundation (NAF) to improve our website infrastructure! As you know, SCAsource is run by a Read More…
The SCAsource team is pleased to announce that we have become a partner of the Ataxia Global Initiative (AGI)! The AGI is an international collaboration to assist the development of Read More…
Wishing you and your families a happy and safe holiday season! We will be back in January 2021 with new content. Hope you have a fantastic new year! Read More…
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