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Snapshot: O que é terapia genética?

Terapia genética significa utilizar ácidos nucleicos para tratar uma desordem genética. Esses ácidos nucleicos podem ser desenhados em uma variedade de formas para alcançar um mesmo propósito terapêutico. Ferramentas de terapia genética podem ser utilizadas para corrigir um gene mutante através de uma das três formas: Expressão de uma cópia saudável Read More…

¿Qué es el nistagmus?

El nistagmus, también conocido como ataxia ocular, es un término que se refiere al movimiento incontrolable del ojo, generalmente un ciclo repetitivo de movimiento lento en una dirección específica seguido de un ajuste rápido de regreso al centro. La raíz de este movimiento reside en un reflejo normal que usamos Read More…

Snapshot: What is the Pole Test?

The pole test is a common and straightforward test to assess motor coordination in mice. While ataxia might be easy to see in patients, it is not always as apparent in ataxia mouse models. Therefore, this fast and simple test is important for researchers to measure disease severity. It is Read More…

Snapshot: What is N-acetylcysteine?

What is N-acetylcysteine used for? Cysteine is an amino acid that is used as a building block in our bodies to make proteins. We consume cysteine in our diets through protein-rich foods, like beef or lentils. N-acetylcysteine is a chemical derivative of cysteine. This means which means that N-acetylcysteine contains Read More…

Snapshot: What is Nystagmus?

Nystagmus, also known as ocular ataxia, is a term that refers to uncontrollable eye movement- usually a repetitive cycle of slow movement in a specific direction followed by a quick adjustment back to center. The root of this movement lies in a normal reflex that we use every day: the Read More…

Snapshot: What is Transcranial Direct Current Stimulation (tDCS)?

Transcranial Direct Current Stimulation (tDCS) is a non-invasive method of brain stimulation. It promotes or inhibits activities in specific parts of the brain. tDCS is an experimental treatment that has been shown to result in changes in motor, cognitive and behavioural activities. It may be a valuable tool for the Read More…

Snapshot: What is Riluzole?

Riluzole, often sold under the trade name Rilutek, is a medication used for the treatment of amyotrophic lateral sclerosis (ALS). ALS is a fatal neurodegenerative disease that mainly affects neurons controlling muscle movements. The drug was approved by the FDA (1995), Health Canada (1997), and the European Commission (1996). It Read More…

Snapshot: What is Cerebrospinal Fluid (CSF)?

Public transit may not be the first thing that comes to mind when we think about the brain, but it’s a great way to understand how all the parts of the central nervous system work together. Nutrients, hormones, and other important molecules (the passengers) need to get on and off Read More…

Snapshot: What is Neurogenesis?

Neurons are the cells that serve as building blocks of the nervous system. The brain contains an enormous variety of neurons, and they all need to get a start somewhere. The process by which neurons are formed is called neurogenesis. When does neurogenesis happen? Nearly all neurogenesis occurs before the Read More…

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