Luca Marsili

After completing my residency training in Neurology in Italy, I pursued a PhD in Clinical Neuroscience, which solidified my commitment to both clinical practice and research in the field of movement disorders. Throughout this period, my work focused on three key areas: (a) the clinical phenomenology and genetic underpinnings of movement disorders; (b) therapeutic strategies and clinical challenges in Parkinson’s disease, atypical parkinsonisms, and other movement disorders; and (c) the neurophysiology of the human motor system.

As a co-investigator, I participated in several phase III multicenter randomized clinical trials in Parkinson’s disease, which enhanced my understanding of clinical trial design and the complexities of therapeutic development. These experiences deepened my interest in the clinical management of movement disorders and the investigation of their underlying pathophysiology.

Since relocating to the United States in 2017, my research focus has evolved to include the genetic foundations of movement disorders. I have taken a leading role in the Telegenetic Counseling Program for rare movement disorders at our center in Cincinnati. This innovative service provides comprehensive genetic testing and counseling for patients with rare conditions, bridging clinical care with molecular diagnostics and personalized medicine. In 2024, I was appointed faculty at the University of  Cincinnati and I started a Genetics Clinic where I follow patients with Ataxia and any other genetic movement disorders.

Through these diverse experiences, I have developed a strong commitment to advancing our understanding of Ataxia and improving patient outcomes through both clinical excellence and translational research. I am eager to continue contributing to this field at the intersection of neurology, genetics, and patient-centered care.